Imagine designing a drug to attack a parasite, only to realize that the parasite has a protein that looks a lot like one in your own body. Now you have a problem. The parasite I looked at, Schistosoma mansoni, has its own version of a protein called acetylcholinesterase, or AChE. Humans have AChE too. So if AChE is going to be targeted, how do you make sure you're targeting the parasite and not yourself? That was the question I wanted to investigate. Same Protein, Not Quite t